An article in Volume 233, 2019 of Social Science & Medicine discusses the potential weaknesses of systematic reviewes, even when they are following the PRISMA Guidelines for such reviews. The authors "advocate that SR teams consider potential moderators (M) when defining their research problem, along with Time, Outcomes, Population, Intervention, Context, and Study design (i.e., TOPICS + M). We also show that, because the PRISMA reporting standards only partially overlap dimensions of methodological quality, it is possible for SRs to satisfy PRISMA standards yet still have poor methodological quality. As well, we discuss limitations of such standards and instruments in the face of the assumptions of the SR process, including meta-analysis spanning the other SR steps, which are highly synergistic: Study search and selection, coding of study characteristics and effects, analysis, interpretation, reporting, and finally, re-analysis and criticism". Read more...
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A scoping review of the research on school health and development programs in low resource countries was published in Issue #5, 2016 of Health Education Research. "We included 30 studies meeting specific criteria: (i) studies mainly targeted school going children or adolescents; (ii) admissible designs were randomized controlled trials, controlled before-after studies or interrupted time series; (iii) studies included at least one measure of impact and (iv) were primary studies or systematic reviews. We found that school-based interventions can be classified in two main categories: those targeting individual determinants of health such as knowledge, skills and health behaviors and those targeting environmental determinants such as the social and physical environment at the school, family and community level. Findings suggest that a comprehensive approach addressing both individual and environmental determinants can induce long-term behavior change and significantly improve health and educational outcomes. We highlight the need for further study of the long-term impact of school-based interventions on health outcomes in developing countries." ISHN has been collecting a number of similar reviews that examine different applications of the "School Health & Nutrition" programs/approach to this context. Our recent ISHN report to Members-Subscribers includes similar conclusions to those reached in this review; that there are several "multi-intervention programs" addressing issues such as water-sanitation-hygiene (WASH), school feeding and the prevention of infectious diseases that produce changes both to the conditions in schools as well as student health & behaviours. Read more >> (This item is among the 5-10 highlights posted for ISHN members each week from the ISHN Member information service. Click on the web link to join this service and to support ISHN)
This blog has been identifying the limits of RCT's & systematic reviews. RCT's are problematic when seeking to assess complex, multiple interventions that develop over several years across several systems, agencies and professionals. An editorial in the October 2015 Issue of Journal of Epidemiology & Community Health continues this discussion by arguing for more use of "pragmatic, formative evaluations" when implementing a complex intervention. The editorial begins: "Recently published guidance on process evaluations by the Medical Research Council's (MRC's) Population Health Sciences Research Network (PHSRN) marks a significant advance in the evaluation of complex public health interventions. In presenting programmes as not just a set of mechanisms of change across multiple socioecological domains, but as an interaction of theory, context and implementation, the guidance extends the remit of evaluation. Process evaluations have emerged as vital instruments in these changing needs through modelling causal mechanisms; identification of contextual influences and monitoring fidelity & adaptations." They go on to say: "One particular conceptual space that needs to be carved out is pragmatic formative process evaluation, defined as the application of formative process evaluation criteria to interventions that have ostensibly been formulated, and are likely in routine practice, but have not been subjected to rigorous evaluation. Moreover, even where some understanding of the theory of change is present, it is unlikely that the unintended consequence of interventions will have been sufficiently explored. For example, our recent evaluation of a school-based social & emotional learning intervention, which had been recommended by the Welsh school inspectorate indicated a number of potential iatrogenic effects due to a stigmatising process". Read more>> (An item from the ISHN Member information service)
Since about 2005, our attention in school health and social development has included a focus on the country, community and neighbourhood contexts as a key factor in selecting the issues to be addressed, the programs to be used and the capacities to be strengthened. ISHN has worked with others to develop frameworks for indigenous communities, disadvantaged communities in high resource countries and more recently, in low resource countries. But those efforts are ahead of the good research required to guide practice. So we were pleased to note the article in the September 2015 Issue of Implementation Science describing a project to Identify the domains of context important to implementation science. "This research program will result in a framework that identifies the domains of context and their features that can facilitate or hinder: (1) healthcare professionals’ use of evidence in clinical practice and (2) the effectiveness of implementation interventions. The framework will increase the conceptual clarity of the term “context” for advancing implementation science, improving healthcare professionals’ use of evidence in clinical practice, and providing greater understanding of what interventions are likely to be effective in which contexts." Read more>> (An item from the ISHN Member information service)
Several articles in Issue #5, 2015 of Administration and Policy in Mental Health and Mental Health Services Research provide insights and methods for significantly changing the research in school health promotion and social development. Most studies, often replicated again and again, measure the linear impact of a selected intervention (instructional program, policy or service) delivered at the school level only on a behaviour or problem. Sometimes, combinations of interventions delivered at the school level, usually aimed at one or two behaviours or combination of problems, are evaluated for a short period of time. Rarely, we see attempts to group these singular or limited intervention studies into a health promoting schools model and assess whether the HPS model works (Again, the assessments almost never extend beyond the school to include clinics or other agencies or upwards into the health, education and other systems. Implementation research, a new type of work in health promotion and social development, has also been limited to this narrow, singular and front-line scope. This is because of the costs and complexity of multi-level research in large systems. As noted in the introduction to this set of articles in this journal "Implementing evidence-based and innovative practices, treatments, and services in large systems is highly complex, and has not, until recently, been guided by empirical or theoretical knowledge. Mixed method designs and approaches have been proposed to promote a more complete and efficient way of understanding the full range of factors that influence the dissemination and implementation of evidence-based innovations in large systems.This special issue provides both an overview of mixed methods designs and approaches, as well as applications and integration of sophisticated sampling, statistical methods and models (borrowed from various fields such as anthropology, statistics, engineering and computer science) to increase the range of solutions for handling the unique challenges of design, sampling, measurement, and analysis common in implementation research. In the six papers in this special issue, we describe conceptual issues and specific strategies for sampling, designing, and analyzing complex data using mixed methods. The papers provide both theoretically-informed frameworks, but also practical and grounded strategies that can be used to answer questions related to scaling-up new practices or services in large systems." Read more>> (An item from the ISHN Member information service)
Several articles in Issue #8-9, 2015 of Substance Use & Misuse are part of a special Issue describing progress (and not) in substance abuse. The title of the issue says it well "Fifty Years Later: Ongoing Flaws and Unfinished Business". The articles include some great insights into the debates, many ongoing, within this filed. They include a discussion of the politics in dropping the term "addiction" and turning to problematic or misuse; the failure to address discrimination as a cause of substance abuse; the clever marketing that underlies "evidence-based practices" and how the concept of "gateway drug" needs to be retired. Another article likes drug use by young people in Hong Kong to the profound economic and social changes that have occurred there in the past five decades. One not to be missed is an article discussing how negative (focus on risk and problems) and positive (focus on assets and youth development) models in adolescent substance abuse prevention are found wanting. The over reliance on RCT studies as the "gold standard" in knowledge development is also debated. Another article describes the ongoing challenges associated with implementation and maintenance of effective programs. Other deal with context, the challenges of integrated programming, evidence-based vs local programs, and community-school cooperation. n brief, the special issues captures much of the recent history and challenges in substance abuse prevention but it also offers insight into prevention and promotion more generally. Read More>> (An item from the ISHN Member information service)
(An item from the ISHN Member information service) Two articles in Volume 183, 2015 of Journal of Affective Disorders report on the use of the Delphi method (used to develop consensus) to list and assess the value of interventions to reduce the risk of adolescent depression and on parenting strategies to reduce childhood depression and anxiety. The first article used a literature search to identify 194 potential interventions. "These were presented over three questionnaire rounds to panels of 32 international research and practice experts and 49 consumer advocates, who rated the preventive importance of each recommendation and the feasibility of their implementation by adolescents. 145 strategies were endorsed as likely to be helpful in reducing adolescents׳ risk of developing depression by ≥80% of both panels. Endorsed strategies included messages on mental fitness, personal identity, life skills, healthy relationships, healthy lifestyles, and recreation and leisure. " The second article used a literature search identified 289 recommendations for parents which were then presented to a panel of 44 international experts over three survey rounds, who rated their preventive importance. "171 strategies were endorsed as important or essential for preventing childhood depression or anxiety disorders by ≥90% of the panel." Some researchers contributed to both articles. The ISHN web site (www.schools-for-all.org) uses a similar combination of research-based evidence and the views of experienced practitioners, descition-makers and advocates and publishes the content in a Wikipedia style web site. Read more>>
(An item from the ISHN Member information service) ISHN has been discussing the limits systematic review in this blog. An article in Issue #3, 2015 of Evidence & Policy extends our skepticism by examining how various "evidence tools (health impact assessments, systematic reviews and cost-benefit studies) are used, misused and misinterpreted in the real world of public decision-making. The authors conclude that "Each has been promoted as a means of synthesising evidence for policy makers but little is known about policy actors' experiences of them. Employing a literature review and 69 interviews, we offer a critical analysis of their role in policy debates, arguing that their utility lies primarily in their symbolic value as markers of good decision making." Not having access to the full text of that article, we did find a very similar version online that includes this statement "‘evidence tools’ can be important means of supporting policy decisions because they appear to be objective and credible (or at least more objective and credible than single studies may be). In addition, the interviewee suggests that ‘evidence tools’ employing quantitative data and providing clear and simple ‘answers’ to policy questions represent ‘gold dust’ to policymakers, who are often desperate for some sense of certainty within complex (and often contested) debates. " They go on to say that " All this leads us to conclude that ‘evidence tools’ represent means of drawing policymakers’ attention to particular kinds of evidence (and, implicitly, away from other kinds). As such, they might best be understood as ‘research-informed advocacy tools’ constructed and employed by actors (researchers using their black magic) working to inform the policy process. Read more>>
(An item from the ISHN Member information service) An article in Issue #6, 2015 of American Journal of Public Health contends that the 200+ health awareness days, weeks and months do little to promote health or well-being. Schools are often a big part of these awareness activities, often viewing the participation in these days to be akin to addressing the problem. The authors "contend that health awareness days are not held to appropriate scrutiny given the scale at which they have been embraced and are misaligned with research on the social determinants of health and the tenets of ecological models of health promotion. We examined health awareness days from a critical public health perspective and offer empirically supported recommendations to advance the intervention strategy. If left unchecked, health awareness days may do little more than reinforce ideologies of individual responsibility and the false notion that adverse health outcomes are simply the product of misinformed behaviors. Read more>>
(An item from the ISHN Member information service) ISHN has been critical of the "training then hoping" strategies that are often the default option for improving practice and introducing new health and social programs in schools. This blog article pulls together three recent articles on how health professionals use knowledge (or not) when modifying their practice. The first article, published in the May 2015 Issue of the International Journal for Equity & Health, "was to identify existing knowledge to action models or frameworks and critically examine their utility for promoting or supporting health equity. Forty-eight knowledge to action models or frameworks were identified. All of the models were then assessed across six characteristics relevant for supporting health equity. While no models scored full marks, the highest scoring models were found to have features relevant to advancing health equity. In the assessment, we propose six characteristics that could be important markers: 1) an explicit mention of equity, justice or similar concept; 2) the involvement of various stakeholders; 3) an explicit focus on engagement across multiple sectors or disciplines; 4) the use of an inclusive conceptualization of knowledge; 5) the recognition of the importance of contextual factors; and, 6) a proactive or problem-solving focus. Specific populations, topics and solutions are marginalized, ignored, or not acted upon when, for example, only certain knowledge is considered valuable, when we don’t have a specific focus on equity or justice, and when we don’t work across sectors or consider contextual determinants of health." The authors concluded that "Each could be strengthened in some way to make them more useful in supporting health equity by considering the six characteristics used in this review. Of particular interest is knowledge brokering as well as the use of holistic and cross-sector models of knowledge to action that consider environmental and contextual determinants. These are specific future avenues identified in this project." In other words, using "knowledge to action" frameworks, even if they are adapted to suit equity purposes, was not sufficient to improve efforts related to equity.
The second article, published in Issue #1, 2015 of Health Technology Assessment, was to identify the impacts and likely impacts on health care, patient outcomes and value for money of Cochrane Reviews published by 20 NIHR-funded CRGs during the years 2007–11. The authors note that "we found 40 examples where reviews appeared to have influenced primary research and reviews had contributed to the creation of new knowledge and stimulated debate. Twenty-seven of the 60 reviews had 100 or more citations in Google Scholar™ (Google, CA, USA). Overall, 483 systematic reviews had been cited in 247 sets of guidance. This included 62 sets of international guidance, 175 sets of national guidance (87 from the UK) and 10 examples of local guidance. Evidence from the interviews suggested that Cochrane Reviews often play an instrumental role in informing guidance, although reviews being a poor fit with guideline scope or methods, reviews being out of date and a lack of communication between CRGs and GDs were barriers to their use. Cochrane Reviews appeared to have led to a number of benefits to the health service including safer or more appropriate use of medication or other health technologies or the identification of new effective drugs or treatments. However, whether or not these changes were directly as a result of the Cochrane Review and not the result of subsequent clinical guidance was difficult to judge." The authors of this second article concluded that " The clearest impacts of Cochrane Reviews are on research targeting and health-care policy, with less evidence of a direct impact on clinical practice and the organisation and delivery of NHS services". In other words, systematic reviews and possibly even the practice guidelines that try to use such Cochrane Reviews as their basis, may or may not affect practice. The third article, published in the April 2015 Issue of the Cochrane Database of Systematic Reviews, examined "whether tailored intervention strategies are effective in improving professional practice and healthcare outcomes. We compared interventions tailored to address the identified determinants of practice with either no intervention or interventions not tailored to the determinants...Attempts to change the behaviour of health professionals may be impeded by a variety of different barriers, obstacles, or factors (which we collectively refer to as determinants of practice). Change may be more likely if implementation strategies are specifically chosen to address these determinants." The authors conclude that "The findings continue to indicate that tailored interventions can change professional practice, although they are not always effective and, when they are, the effect is small to moderate. There is insufficient evidence on the most effective approaches to tailoring, including how determinants should be identified, how decisions should be made on which determinants are most important to address, and how interventions should be selected to account for the important determinants. In addition, there is no evidence about the cost-effectiveness of tailored interventions compared to other interventions to change professional practice." Our take away from these three and other studies we have been reading is that knowledge about better practices or better programs is insufficient to implement or sustain improvements in professional or organizational practices. The answers lie within the organizational or community context, likely based on their current core mandates, perceived and real constraints, traditions and routines and current system-level and adopter concerns at various levels. In other words, we may need to make a significant shift away from "evidence-based practice" towards auch better understanding of "practice-based experience". (An item from the ISHN Member information service) In a series of ISHN commentaries in this blog, we have discussed the limits of RCT-based studies and the mistaken notion that they represent the "gold standard" when considering modifications to practice. An article in Issue #2, 2015 of Health Education Research continues the discussion with a small scale study examining the evidence that is valued most and used by health promotion practitioners. The authors report that "Although there is a general consensus that adopting an evidence-based approach is necessary for practice, disagreement remains about what types of evidence practitioners should use to guide their work. An empirical understanding of how practitioners conceptualize and use evidence has been lacking in the literature. In this article, we explore (i) practitioners’ purposes for using evidence, (ii) types of evidence they valued, and (iii) qualities that made evidence useful for practice. 58 semi-structured interviews and 250 h of participant and non-participant observation were conducted with 54 health promotion practitioners working across New South Wales, Australia. Interviews were recorded and transcribed, and field notes were written during the observations; these were analysed using Grounded Theory methods. Practitioners used evidence for practical and strategic purposes, and valued four different types of evidence according to their relevance and usefulness for these purposes. Practitioners’ ideal evidence was generated within their practice settings, and met both substantive and procedural evaluation criteria. We argue that due to the complex nature of their work, practitioners rely on a diverse range of evidence and require organizational structures that will support them in doing so." Read more>>
(From the ISHN Member information service) ISHN has recent published several Commentaries on the value of Random Controlled Trials (RCT's) in health promotion/social development. Two articles in Issue #1, 2015 of Global Health: Science & Practice continues this discussion. The first article "takes issue with Shelton's (The Editor of the Journal) previous article that “randomized controlled trials (RCTs) have limited utility for public health” They argue that "setting RCTs in opposition to other systematic approaches for generating knowledge creates a false dichotomy, and it distracts from the more important question that Shelton addresses—namely, which research method is best suited for the question at hand?" They conclude with the traditional defence of RCT's that "It is imperative for public health practitioners to answer definitively, “Does it work?” before asking, “How can it be made to work practicably at scale?” In the rebuttal article, the author states that "“Does it work” is always affected by context. The paradigm Hatt et al. put forward asserts that one strength of randomized trials is to answer definitively, “Does it work?” But for the kinds of complex programs public health must muster, there is generally no absolute answer to that question" This article states that "RCTs are only one piece of the picture in triangulating evidence for public health programming." but, he also goes on to say that "While I really do appreciate randomized studies, perhaps my biggest concern is the “hierarchy” whereby some colleagues place controlled trials at the top of a pyramid as manifestly the best evidence. For understanding public health programming, I see that as quite misguided. Randomized studies help us to understand some things, but they are only one piece of the picture in “triangulating” evidence for programming. And evidence from real-world programming is especially key." Read more>>
(From the ISHN Member information service) An excellent illustration of a procedure to select evidence-based interventions to promote health is described in Issue #1, 2015 of Environmental Health Review. ISHN recommends the use of this type of planning tool but also suggests that, despite the rigour within this procedure used to select relevant research on better practices, other steps need to be taken to test our underlying assumptions before we begin as well as use our common sense in assessing the fit between the planned intervention and our local context, especially in regards to likely barriers that may be prevalent in our local communities, states or countries.
The illustration used in the journal article is focused on an urban setting, wherein the public health practitioners are looking for urban planning interventions to increase physical activity among children and adults in the community in response to rising obesity rates. The article takes the reader through several planning steps to identify such urban planning tools, eventually pointing to a credible research review published by the CDC in the United States that suggest that "Community-scale urban design and land-use regulations, policies, and practices" such as zoning regulations and building codes, and environmental changes brought about by government policies or builders’ practices. The latter include policies encouraging transit-oriented development, and policies addressing street layouts, the density of development, the location of more stores, jobs and schools within walking distance of where people live as well as "street-scale urban design and land use approaches" in small geographic areas, generally limited to a few blocks, such as improved street lighting or infrastructure projects that increase the ease and safety of street crossing, ensure sidewalk continuity, introduce or enhance traffic calming such as center islands or raised crosswalks, or enhance the aesthetics of the street area, such as landscaping can improve levels of physical activity. Once these two types of interventions are identified in the procedure, the remaining steps suggest the involvement of stakeholders, program development and building in evaluation and feedback mechanisms. One section of the procedure suggests "Assessing Applicability and Transferability of Evidence" but the focus in that section is on how the knowledge about the intervention can be transferred successfully to policy-makers and practitioners and mentions real-barriers related to feasibility such as costs, resources and other practical factors only briefly. We suggest here that this excellent illustration of a procedure to select an intervention to address a problem needs to be accompanied by at least three other processes. The first of these is to test our assumptions about the type of outcome we are seeking. The illustration in this article, where the fictional planners decide in advance that increased physical activity can prevent or reduce obesity and overweight is actually reflective of many real-life planners, who have done the same. The trouble is that there is increasing evidence, including from sources such as the CDC and the centre which has published this guide to selecting interventions, that increased physical activity alone, will have little impact on body weight unless it is very intense, well beyond the scope of the average person. The second process we suggest is a real hard look at the resources available in the community or organization. The research reviews identified in the article did note these barriers in their study. The barriers to community scale interventions include "1) changing how cities are built given that the urban landscape changes relatively slowly, 2) zoning regulations that preclude mixed-use neighborhoods, 3) cost of remodeling/retrofitting existing communities, 4) lack of effective communication between different professional groups (i.e., urban planners, architects, transportation engineers, public health professionals, etc.), and 5) changing behavioral norms directed towards urban design, lifestyle, and physical activity patterns" The real world barriers to street scale changes include: "the expense of changing existing streetscapes. In addition, street-scale urban design an land use policies require careful planning and coordination between urban planners, architects, engineers, developers, and public health professionals. Success is greatly enhanced by community buy-in, which can take time and effort to achieve. Inadequate resources and lack of incentives for improving pedestrian-friendliness may affect how completely and appropriately interventions are implemented and evaluated". The article suggests that the local context is an established urban setting. In most established cities, it is very difficult to make major changes in existing neighbourhoods, especially in these days where priority concerns might very well be crime, traffic and aging infrastructure. This real world observation leads us to the third major consideration that should be used in conjunction with this procedure to select evidence-based interventions. The third consideration needs to be an in-depth understanding of the core mandates, constraints and current concerns of the system that will carry the major part of the burden in implementing the intervention. In this case, it is the municipality. There are lots of examples of how such systems analysis can be done, but we close this ISHN Commentary with an appropriate example, also found by the same centre that has created this procedure for identifying evidence-based interventions. This systems planning guide that they suggest is from the province of Alberta, which suggests that program planners consider the characterisitcs of the system that will will host the intervention. These include the leadership, organization "slack" in committed vs available resources, staffing, time for implementation and more. In school health promotion, ISHN is pleased to be pat of a global dialogue being led by educators in regards to how health and social programs can be better integrated within education systems. We suggest that before we select an intervention from the research, we seek to truly understand the system that will carry the intervention over the long term. We also suggest we look closely ar practical barriers and that we check our assumptions. Read more>> (From the ISHN Member information service) Recently we have been discussing the value and limits of Random Control Trials (RCT) and subsequent systematic reviews based on those trials. Although it does not discuss school-related programs directly, an article the February 2015 issue of Children and Youth Services Review continues this discussion, noting the need to control or at least accurately describe the control groups used in comparison with the intervention being tested. The authors ask if "Does allocation to a control condition in a Randomized Controlled Trial affect the routine care foster parents receive? And, of course, the answer is yes. "Strengthening Foster parents in Parenting’ (SFP) is a support program for foster parents who care for foster children with externalizing problem behavior. Its effectiveness was examined with a Randomized Controlled Trial (RCT). In this paper, we examine the treatment as usual (TAU) that was offered in the control condition of this RCT. For this purpose, the TAU from the SFP control group was compared with TAU provided to a similar group of foster parents outside any RCT. Our results show that TAU is diverse and varies widely. Furthermore, being part of the control condition was positively associated with both the counseling frequency from the foster care services and with external help-seeking behavior (finding and using additional support). In order to prevent condition contamination in future trials, TAU should be clearly described and standardized, and treatment fidelity should be carefully monitored." We suspect that this natural inclination to improve performance while being part of a research study will also affect school-based studies. Further, as the authors note (and as we have commented before, the Treatment As Usual" condition, even as is, may actually be quite close to the intervention being tested. Read more>>
(From the ISHN Member information service) A meta-analysis in Volume 56, 2015 of Preventive Medicine concludes that school-based nutrition education can affect the BMI of children. Unlike interventions aimed at single behaviours such as physical activity, the authors of this review suggest that a focus on healthy eating may be the best course for reducing body weight. The authors "conducted a systematic search of 14 databases until May 2010 and cross-reference check in 8 systematic reviews (SRs) for studies published that described randomized controlled trials conducted in schools to reduce or prevent overweight in children and adolescents. An additional search was carried out using PubMed for papers published through May 2012, and no further papers were identified. Body mass index (BMI) was the primary outcome. The title and abstract review and the quality assessment were performed independently by two researchers. From the 4888 references initially retrieved, only 8 met the eligibility criteria for a random-effects meta-analysis. The total population consisted of 8722 children and adolescents. Across the studies, there was an average treatment effect of − 0.33 kg/m2 (− 0.55, − 0.11 95% CI) on BMI, with 84% of this effect explained by the highest quality studies. This systematic review provides evidence that school-based nutrition education interventions are effective in reducing the BMI of children and adolescents" Read more>>
(From the ISHN Member information service) We have often questioned the over-reliance on RCT studies and systematic reviews of these studies in these ISHN Commentaries. One of our concerns has been the fact that the control group in many studies often has an existing intervention (policy, program or practice) that is quite similar to the new intervention being tested. Often, the authors of the study conclude that the new program works or not and then the systematic review of these types of studies concludes whether this type of intervention is effective. The assumption is that the new program can be treated as a medication (dose, intensity, duration) and be compared with situations where o such program exists. In fact, these comparisons are being made to potentially very similar conditions affecting the control groups. These studies are really only able to conclude that the new intervention being tried is better, worse or similar to the existing situation. An article in the March 2015 Issue of Addiction discusses this weakness in RCT/Systematic Review methods and asks the question: "Compared with what? An analysis of control-group types in Cochrane and Campbell reviews of psychosocial treatment efficacy with substance use disorders" They then go on to make this argument: "A crucial, but under-appreciated, aspect in experimental research on psychosocial treatments of substance use disorders concerns what kinds of control groups are used. This paper examines how the distinction between different control-group designs have been handled by the Cochrane and the Campbell Collaborations in their systematic reviews of psychosocial treatments of substance abuse disorders. Methods We assessed Cochrane and Campbell reviews (n = 8) that were devoted to psychosocial treatments of substance use disorders. We noted what control groups were considered and analysed the extent to which the reviews provided a rationale for chosen comparison conditions. We also analysed whether type of control group in the primary studies influenced how the reviews framed the effects discussed and whether this was related to conclusions drawn. Results The reviews covered studies involving widely different control conditions. Overall, little attention was paid to the use of different control groups (e.g. head-to-head comparisons versus untreated controls) and what this implies when interpreting effect sizes. Seven of eight reviews did not provide a rationale for the choice of comparison conditions. Conclusions Cochrane and Campbell reviews of the efficacy of psychosocial interventions with substance use disorders seem to underappreciate that the use of different control-group types yields different effect estimates. Most reviews have not distinguished between different control-group designs and therefore have provided a confused picture regarding absolute and relative treatment efficacy. A systematic approach to treating different control-group designs in research reviews is necessary for meaningful estimates of treatment efficacy." Read more>>
(From the ISHN Member information service) An editorial in the January 2015 issue Cochrane Database Systematic Reviews discusses the challenges of reviews of complex interventions such as school health promotion. Although the editorial is discussing coordinated case management of dementia patient care, the comments will likely apply to the complexity of reviewing the variable, multiple, coordinated interventions required in school health promotion.
The authors suggest that "Guidelines have recommended the use of case management but are cautious about the evidence, judged as at least partially inconclusive.There is also uncertainty about the most suitable components of case management interventions.This is no surprise as case management is a prototypical example of a complex intervention. There is complexity in the intervention components as well as in the theoretical background of the intervention, the implementation context, and the targeted outcomes. As with many complex interventions, case management also targets more than one recipient: people with dementia and/or their carers. The challenges of synthesising the evidence for complex interventions have been acknowledged by Cochrane, with a recent series of articles forming the basis for an upcoming new chapter in the Cochrane Handbook for Systematic Reviews of Interventions." The authors laud the particular review of dementia with comments that could be applied to the variations in school health promotion; " Comprehensive tables allow readers to compare the goals of case management interventions, components of case management and control interventions, methods of intervention implementation, tasks and components of case management, and outcome measures used. Interventions are also categorised into three different approaches to case management. Still, for many studies there is not enough information to clearly describe what has been done. Also, case management interventions were often implemented as a part of wider health system changes, making it more difficult to attribute observations to case management, let alone to distinct components of case management interventions.". The authors also make suggestions for reviews of complex interventions that also apply to school health and other school-related strategies; "Guidance on conducting systematic reviews of complex interventions often demands the inclusion of further studies to allow for in-depth descriptions of study components and the context and process of implementing the intervention. This frequently requires the inclusion of mixed-method or qualitative studies that could help to disentangle the intervention components and their distinct roles. While this undoubtedly adds to Cochrane authors' already demanding workload, it seems essential if the most meaningful use is to be made of the data. Reporting is a problem, and information is often difficult or even impossible to acquire. Recent reporting guidelines may help authors look for important aspects concerning the intervention (TIDieR guideline) or the whole process of complex intervention development and evaluation (CReDECI guideline)" They also mention other problems; "Apart from the problems described above, the present review suffers from the fact that most studies are fairly small, with fewer than 100 participants per group in all but one study". We would add that the time period for assessing school health approaches is also problematic. A truly comprehensive, ecological and systems-based approach to SH does more than examine a few schools or some selected interventions. it is an approach that is developed over several years at a national or sate level, with the delivery of multiple policies, funding, personnel and programs from several ministries, local agencies/school boards and then local professionals as well as the people working in the school building. Indeed, reviews of school health promotion and social development are actually far more complex than the one discussed in this editorial, which examines coordinated case management of a single health problem. It is in the light of this January 2015 Cochrane editorial that we can turn to two major recent and previous reviews of school health promotion (Langford et al, 2014; Stewart-Brown, 2006) and understand better why both of these reviews as well as others conclude that SH promotion is promising but there is insufficient evidence. For further discussion, readers might want to listen to our recent October 23, 2014 ISHN webinar with the authors of the most recent review, as it discusses the limits of RCT studies and the ensuing systematic reviews even further. We hereby challenge researchers and research funding organizations to address this challenge, perhaps beginning with the impending Cochrane Handbook Chapter on complex interventions. |
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